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LC/MS/MS Rapid Toxicology Screening System
Ver.3
This system improves the efficiency of simultaneous LC/MS/MS analysis methods by allowing the user to start analysis without time-consuming steps such as consideration of separation conditions and MS parameter optimization. Rapid simultaneous analysis methods with analysis times under 15 mins are included for 235 compounds including drugs of abuse, psychoneurotic drugs and sedatives. The system also provides optimised conditions for synchronised survey scans used in screening measurements (conditions adopted for the product ion spectrum as a threshold value for the intensity in MRM).
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Control Relays
Drexelbrook manufactures a supporting line of control relays that are developed especially for use as safe, reliable, economical original equipment components in many different types of commercial and industrial products.Designed to operate from electrodes or probes contacting conductive liquids, our control relays are ideally suited for level control applications in such products as vending, dispensing, ice-making machines, water softeners, dishwashers, and coffee makers, plus many types of operating equipment in the food, drug, dairy, brewing, distilling and chemical processing industries.
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Microcalorimeters
TA Instruments’ Isothermal Titration Calorimetry (ITC), Differential Scanning Calorimetry (DSC), and Isothermal Calorimetry systems are powerful analytical techniques for in-depth characterization of molecular binding events and structural stability. Thermodynamic binding signatures not only reveal the strength of a binding event, but the specific or nonspecific driving forces involved. Structural stability profiles from DSC reveal strengths and weaknesses in higher order structure and define the behavior of individual domains and their interactions. The TA Instruments Affinity ITC, Nano ITC and Nano DSC provide the performance, reliability and ease-of-use required for the most demanding applications in drug discovery, protein-protein interactions, structure-function characterization and more.
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Multi-omics Analysis Package
The Multi-omics Analysis Package, developed for metabolic engineering applications, provides the ability to automatically generate metabolic maps and perform a variety of data analysis for the vast data generated in fields like metabolomics, proteomics and flux analysis. It offers a powerful platform to support drug discovery, bioengineering and other life science research applications.
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Application Specific LC Systems
Antimicrobial Screening System
Screening of 24 Synthetic Antimicrobial Compounds That Remain in Meat Synthetic antimicrobial agents are used as animal drugs and feed additives and they are known to remain in the body of farm animals. Residue limits prescribing the safe ingestible amounts of such agents have been set so that people can safely eat meat and processed meat products. Thanks to a pretreatment method*1 that minimizes the influence of impurities in meat (beef, pork, and chicken muscle), LC system enables screening of 24 synthetic antimicrobial compounds, which are regulated in Japan, Europe, and other regions, remaining in meat. *1: Consumables for pretreatment are not included in the package. They need to be provided by the customer.
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Energy Dispersive X-ray Fluorescence Spectrometer
Pharmaceutical Elemental Impurities Analysis System
Control of Elemental Impurities in Pharmaceuticals In the pharmaceutical industry, the analysis of elemental impurities is necessary to ensure the safety of pharmaceuticals. In December 2014, the "Guideline for Elemental Impurities" (Q3D) was issued by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), consisting of representatives from Europe, the U.S. and Japan. In Japan, the "Guideline for Elemental Impurities in Drug Products" (PFSB/ELD Notification 0930 #4 from the Ministry of Health, Labour and Welfare) was issued, and will be applied to new drug products submitted for approval after April 1 2017. For 24 elements categorized in Class 1 to Class 3, residual quantities in pharmaceutical drug products must be controlled within permissible limits. Although ICP-AES and ICP-MS are used for precise analysis of elemental impurities, X-ray fluorescence spectrometers can be used as an alternative analysis method. This is because they can quantitatively and qualitatively analyze a variety of elements nondestructively, and without chemical pretreatment, unlike ICP-AES and ICP-MS systems. The X-ray fluorescence spectrometry has been adopted as a general method of analysis in the U.S Pharmacopeia and the European Pharmacopoeia. (USP<735>, Ph.Eur.2.2.37)
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Mass Spectrometer
Q Exactive™ Hybrid Quadrupole-Orbitrap
Identify, quantify and confirm more compounds rapidly and with confidence using the Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer. This benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. The Q Exactive Mass Spectrometer is equally useful for untargeted or targeted screening and a broad range of qualitative and quantitative applications in drug discovery, proteomics, environmental and food safety, clinical research and forensic toxicology.
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Handheld Raman Analyzer
TacticID®-1064
The TacticID®-1064 is a field-ready handheld spectral analysis instrument designed for non-contact forensic analysis by safety personnel and first responders, including law enforcement personnel, bomb squads, customs and border patrol, hazmat technicians, and more. The TacticID®-1064 utilizes proven Raman spectroscopy, allowing users to get real-time actionable identification of unknown chemicals, explosives, narcotics, pharmaceutical drugs and many other substances while reducing operational uncertainty and response time. The TacticID®-1064 includes a comprehensive library of over 10,000 substances. In addition, users have flexibility to create their own libraries. By utilizing the 1064nm wavelength, the TacticID®-1064 avoids fluorescence, allowing users to get results in less than 1 minute even when working with tough street samples.
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Photo-Frame Style Smart Signal Detective Jammer
WF-DJ7
Shenzhen Tangreat Technology Co., LTD.
WF-DJ7 is a Painting Smart Signal Jammer.WF-DJ7 is designed mainly used for indoor cellphone signal detection and shielding, such as meeting rooms,border control units, Border Patrol and Drug Enforcement, Customs, Houses, Churches, Courts, Theaters, Offices,classrooms. checkpoint personnel, Hospitals, Recording Studios, Banks, Contract Tendering Rooms, Testing Facilities, Security Services, Military Units, Secret Services, News Conference Scene, Libraries, Museums,Prisons and so on.
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Leak & Seal Integrity Tester
Saicheng Leak Tester is professionally designed for the leakage tests of packages, bottles & pouches for food, drugs, medical instruments, household chemical products, cars, electronic components, stationeries and other industrial products. The instrument also can be used to test seal performance of specimens after falling and compression tests.
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Handheld Narcotics Analyzer
TruNarc™
The global drug problem is increasing, with trafficking of meth, heroin, and emerging threats like fentanyl, and carfentanil, impacting communities worldwide. Law enforcement officials need to quickly identify suspected narcotics in the field to help keep drugs, and drug dealers, off the streets. Now with the expanded v1.7 library, the Thermo Scientific™ TruNarc™ Handheld Narcotics Analyzer enables officers, customs, border control, and other personnel to scan more than 415 suspected illicit substances in a single, definitive test.
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Aerosol Optical Tweezers
Bristol Industrial & Research Associates Ltd
Biral Manufacturers Aerosol Optical Tweezing instruments that offer the ability to study individual particles over indefinite periods. Developed in collaboration with the Bristol Aerosol Research Centre at the University of Bristol the instruments are used in research applications such as atmospheric chemistry, pharmaceutical drug development and basic aerosol research.
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ASCA Pilot Program Participation
Compatible Electronics, Inc. is a testing laboratory participant under the United States Food and Drug Administration’s Accreditation Scheme for Conformity Assessment (FDA ASCA) pilot program. We are listed under ASCA ID# TL-80, TL-81 and TL-82.
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Compact Data Logger for Temperature
NANO-T
Compact size for portable using; integrated USB interface for a convenient connection with PC Visual alarm when temperature or humidity is out of limit Housing material is free of toxicity and halogen, which is in compliance with food and drug safety requirements Suitable for temperature data collection in narrow space
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Generic Drug Development Equipment
One of the fastest ways to understand the pharmaceutical approval process and create a positive cash flow is to develop generic drugs.
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Potentiometric Titrators
Potentiometric titrators provide results which are based on analysis methods that are highly important in the field of electrochemistry and are commonly used for the determination of different organic and inorganic ions in various areas such as process control and environmental, industrial, agricultural analysis and also medicinal drug analysis.
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Cobot Testing System
CT6
The CT6 cobot testing system introduces the benefits of automation to the testing of biomedical devices and components. This system pairs a collaborative robot with a 5900 or 6800 Series universal testing system to increase the efficiency of small to mid-sized testing labs that require a high degree of flexibility in their testing systems. The CT6 is designed to handle a wide range of medical components, including drug delivery, sample collection, and wound closure products.
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Pharmaceutical Analysis Contract Services
Specialist pharmaceutical analysis contract services to support development programs (R&D), regulatory submissions, GMP manufacturing and post-marketing requirements Pharmaceutical analysis contract services can play an important role in your the development process and GMP manufacturing. Concerns about drug safety, costly development programs, complex manufacturing, market demands for evidence-based data and increased regulatory requirements are all issues that can be addressed through a better understanding of your drug substance, drug product or manufacturing process which, in turn, can only be achieved through experienced analytical studies and robust analytical data.
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Comparative Dissolution Tester
CD14 Comparative Dissolution Tester
The Teledyne LABS 14-vessel CD14 Comparative Dissolution Tester runs two methods simultaneously or independently—ideal for bioequivalence studies of generic vs. innovator drug formulations. The 14 stirring positions allow for 6+1 or 12+2 configurations for improved workload efficiency in R&D, formulations, QC, and stability-test labs. With digital temperature probes at 12 positions the CD14 comparative dissolution tester is able to test two different formulations with separate settings for every parameter under the same temperature conditions.
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Multi-sensor Drug & Explosive Detection System
HDK
LDS Hybrid Detection Kit (HDK) - By operating the sensors in parallel, and in real-time, results in much higher probability of detection than the performance of each specific detector. Integrated solution including laser detection technologies, dual Ion Mobility Spectroscopy (IMS) and chemical detection, that operate in synch.
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Trace Evidence Workstation multi-examination
ffTATM
Powerful and versatile, the ffTA provides the forensic scientist with a range of techniques, both new and old, for the examination of trace evidence including: Glass fragments, bodily fluids, gunshot residues, drugs and illicit substances, paint chips, pigments, organic and synthetic fibres.
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pH Ion Meter
pH Ion Meters can be used in research institutions, and at a variety water quality related production sites in the mining, agriculture, forestry and fishery industries, for measuring the ionic concentration and various laboratories for the researches and drug manufacture processes. In addition, it is used in agriculture to measure the salinity levels of surface water and of soil samples and also measure the quality of water.
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Compact Data Logger for Temperature and Humidity
NANO-TH（Medical type）
Compact size for portable using; integrated USB interface for a convenient connection with PC Visual alarm when temperature or humidity is out of limit Housing material is free of toxicity and halogen, which is in compliance with food and drug safety requirements
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Gentle Rocker
The Gentle Rocker™ GR 200i gently agitates the NGI's cup tray to dissolve the active drug in solvent for analysis.
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Radiometric Detectors - Research
Analyzing drug pathways, protecting lab environments, and assessing environmental contamination require instruments with the highest possible sensitivity and specificity. Radiometric detection has long been and still remains to be today, the gold standard for these applications.
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Multi-omics Analysis Package
The Multi-omics Analysis Package, developed for metabolic engineering applications, provides the ability to automatically generate metabolic maps and perform a variety of data analysis for the vast data generated in fields like metabolomics, proteomics and flux analysis. It offers a powerful platform to support drug discovery, bioengineering and other life science research applications.
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Sample Preparation Unit SPU 200i
SPUs (Sample Preparation Unit) provide a fast and easy way to recover active drug from the induction ports and/or preseparators during APSD testing.
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Compact Data Logger for Temperature and Humidity
NANO-TH
Compact size for portable using; integrated USB interface for a convenient connection with PC Visual alarm when temperature or humidity is out of limit Housing material is free of toxicity and halogen, which is in compliance with food and drug safety requirements Suitable for temperature and humidity data collection in narrow space
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Application Specific LC Systems
Co-Sense for Impurities
The FDA draft guidance, "Genotoxic and Carcinogenic Impurities in Drug Substances and Products: Recommended Approaches" prescribes permitted limits for genotoxic impurities in drug substances. These impurities demand more sensitive trace-level analysis than normal impurities. Generally, mass spectrometry methods, such as GC/MS or LC/MS, are used for the high-sensitivity analysis of impurities. However, there is increasing demand for the establishment of a high-sensitivity quantitation method using an absorbance or other conventional detector that is easy to operate and can easily apply existing LC analysis conditions.
